14 CLINICAL STUDIES

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

• The drug's development involved clinical trials with thousands of participants.
• It was first approved by the FDA for ED in 2003 and for BPH in 2011.
• The "Cialis" name is a portmanteau of "continuous" and "quality of life."
• Its long duration of action was a significant advancement over earlier drugs.
• It is on the World Health Organization's List of Essential Medicines.
• This signifies it is one of the most effective and safe medicines needed in a health system.
• In some countries, it is available at a much lower cost than in the United States.
• Traveling with prescription medication requires keeping it in original packaging.
• Having a copy of the prescription or a doctor's note is also recommended.
• It is a widely studied and generally very safe medication when used correctly.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended.

• Cialis 10 mg is not suitable for everyone.
• Men with heart disease should discuss risk with a doctor.
• It’s essential to stay hydrated while taking Cialis.
• Avoid high-fat meals close to dosing time.
• Cialis may improve self-esteem and relationships.
• Overdose can cause significant health issues.
• Always adhere to the prescribed dosage.
• Cialis may be used in combination with psychotherapy.
• Effectiveness may improve with healthy lifestyle changes.
• Keep a medication diary to track effects.
• Report any persistent side effects immediately.

Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how 60 mg cialis often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur.

7.3 Potential for CIALIS to Affect Other Drugs

The makers of these brands are not affiliated with and do not endorse Eli Lilly and Company or its products. Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works.

Alternatives for benign prostatic hyperplasia (BPH)

Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his roman cialis price penis to produce an erection. By controlling the enzyme, tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection. Tadalafil is also used to treat men who have signs and symptoms of benign prostatic hyperplasia (BPH).

Patient resources

BPH is caused by an enlarged prostate. Men with BPH usually have difficulty urinating, a decreased flow of urination, hesitation at the beginning of urination, and a need to get up at night to urinate. Tadalafil will make these symptoms less severe and reduce the chance that prostate surgery will be needed. This medicine is also used to treat erectile dysfunction and signs and symptoms of BPH. Tadalafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension to improve your ability to exercise. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases.

Condition	Caution	Recommended Action
Heart problems	Consult doctor before use	Medical evaluation required
Use with nitrates	Contraindicated	Do not use concurrently
Liver or kidney disease	Caution advised	Dose adjustment or avoid
Hypotension	Caution	Monitor blood pressure
Allergies to tadalafil	Do not use	Check ingredients

If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Product	Dosage	Quantity + Bonus	Price
Cialis Professional	20mg	270 + 6 Pills	623.07€ 593.40€	Buy
Cialis Original	20mg	48 + 4 Pills	224.69€ 213.99€	Buy
Cialis Professional	20mg	180 + 4 Pills	423.11€ 402.96€	Buy
Cialis Generic	10mg	270 + 10 Pills	308.71€ 294.01€	Buy
Cialis Generic	40mg	120 + 8 Pills	206.98€ 197.12€	Buy
Cialis Black	80mg	360 + 20 Pills	639.78€ 609.31€	Buy
Cialis Super Active	20mg	120 + 16 Pills	382.15€ 363.95€	Buy
Cialis Professional	20mg	360 + 6 Pills	807.03€ 768.60€	Buy
Cialis Generic	20mg	270 + 10 Pills	335.21€ 319.25€	Buy
Cialis Generic	60mg	30 + 2 Pills	85.33€ 81.27€	Buy
Cialis Generic	5mg	60 + 4 Pills	86.02€ 81.92€	Buy
Cialis Super Active	20mg	60 + 8 Pills	230.32€ 219.35€	Buy
Cialis Generic	5mg	180 + 10 Pills	159.65€ 152.05€	Buy
Cialis Professional	40mg	20 Pills	110.24€ 104.99€	Buy
Cialis Professional	40mg	90 + 2 Pills	348.59€ 331.99€	Buy
Cialis Professional	40mg	60 + 2 Pills	262.32€ 249.83€	Buy

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Abnormal penis, including curved penis and birth defects of the penis (eg, angulation, cavernosal fibrosis, or Peyronie’s disease) or Sickle-cell anemia (blood disorder)—Use with caution.

Medication details

An erection that won't go away (priapism). Priapism must be treated as soon as possible or lasting damage can happen to your penis, including the inability to have erections. Color vision changes, such as seeing a blue tinge (shade) to objects or having difficulty telling the difference between the colors blue and green. In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including CIALIS) reported a sudden decrease or loss of vision in one or both eyes. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including CIALIS, and call a healthcare provider right away.

What is tadalafil used for?

Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including CIALIS. If you experience these symptoms, stop taking CIALIS and contact a healthcare provider right away. These are not all the possible side effects of CIALIS. For more information, ask your healthcare provider or pharmacist. Store CIALIS at room temperature between 59° and 86°F (15° and 30°C).

Erectile dysfunction explained

Keep CIALIS and all medicines out of the reach of children. Medicines are sometimes prescribed for conditions other than those described in patient information leaflets. This is a summary of the most important information about CIALIS. For more information you can also visit or call 1-877-CIALIS1 (1-877-242-5471). CIALIS® (tadalafil) is a registered trademark of Eli Lilly and Company. May increase risk of unwanted side effects (eg, prolonged erection of the penis).

8.4 Pediatric Use

This is high blood pressure that occurs in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. When the smaller blood vessels in the lungs become more resistant to blood flow, the right ventricle must work harder to pump enough blood through the lungs. Tadalafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart. This medicine is available only with your doctor's prescription.

Erectile dysfunction: what you need to know

This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Crowded optic disc or low cup to disc ratio in the eye (an eye disorder) or Hyperlipidemia (high lipids or fats in the blood) or Non-arteritic anterior ischemic optic neuropathy or NAION (serious eye condition), history of or May increase risk for non–arteritic anterior ischemic optic neuropathy (NAION). Blood vessel problems (eg, aortic stenosis, idiopathic subaortic stenosis) or Heart attack (within the last 3 months) or Heart failure (within the last 6 months) or Retinitis pigmentosa (an inherited eye disorder) or Stroke (within the last 6 months)—Should not be used in patients with these conditions.

• Cialis 10 mg helps increase blood flow to the penis.
• It is not an aphrodisiac; arousal is needed.
• Take Cialis about 30 minutes before sexual activity.
• The medication is effective regardless of food intake.
• A dose adjustment may be necessary for liver issues.
• Men should not plan to take Cialis more than once daily.
• Cialis has been approved by health authorities worldwide.
• Some users report improved erectile quality.
• Cialis may cause muscle pain or nasal congestion.
• Consult your doctor to confirm if Cialis is safe for you.
• Keep out of reach of children and stored properly.

Stomach ulcers—Use must be determined by your doctor. Pulmonary veno-occlusive disease or PVOD (a type of lung disease)—Use with caution. Liver disease, mild or moderate—Use with caution. The effects may be increased because of slower removal of the medicine from the body. Use tadalafil exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Also, do not stop taking this medicine without checking first with your doctor. This medicine comes with a patient information leaflet. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions. You may take this medicine with or without food. Do not split, break, chew, or crush it. Chewable tablets: Chew the tablet completely before swallowing. When using this medicine for erectile dysfunction, the ability to have sexual activity may be improved for up to 36 hours after taking the tablet. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

How to Choose a Dose

Use of Cialis® and Chewtadzy® tablet is not indicated for use in the pediatric population. Safety and efficacy have not been established. Appropriate studies have not been performed on the relationship of age to the effects of Adcirca® and Alyq™ tablet in the pediatric population. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tadalafil in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults. Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body. The dose of this medicine will be different for different patients.

Side Effect	Frequency	Severity	Notes
Headache	Common	Mild to moderate	Usually temporary
Flushing	Common	Mild	Facial redness
Indigestion	Less common	Mild	Related to gastrointestinal
Muscle pain	Rare	Mild	Transient
Nasal congestion	Less common	Mild	Temporary

Follow your doctor's orders or the directions on the label.

Drug Class	Interaction Effect	Notes
Nitrates	Severe hypotension	Contraindicated
Alpha-blockers	Increased risk of blood pressure drop	Use cautiously
CYP3A4 inhibitors	Increased tadalafil levels, risk of side effects	Dose adjustment needed
Other ED medications	Potential additive effect	Avoid combination
Antihypertensives	May enhance blood pressure lowering	Monitor closely

The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets):For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) as a single dose, no more than once a day, taken at the same time each day.Children—Use is not recommended.For treatment of erectile dysfunction (as needed):Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur.